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3D-Printed Isoniazid Tablets for the Treatment and Prevention of Tuberculosis—Personalized Dosing and Drug Release

The aim of the present work was to produce 3D-printed oral dosage forms with a sufficient drug dose displaying various release profiles. Hot-melt extrusion was utilized to produce drug-loaded feedstock material that was subsequently 3D-printed into 6, 8, and 10 × 2.5 mm tablets with 15% and 90% infi...

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Detalles Bibliográficos
Autores principales: Öblom, Heidi, Zhang, Jiaxiang, Pimparade, Manjeet, Speer, Isabell, Preis, Maren, Repka, Michael, Sandler, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373414/
https://www.ncbi.nlm.nih.gov/pubmed/30617660
http://dx.doi.org/10.1208/s12249-018-1233-7