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3D-Printed Isoniazid Tablets for the Treatment and Prevention of Tuberculosis—Personalized Dosing and Drug Release
The aim of the present work was to produce 3D-printed oral dosage forms with a sufficient drug dose displaying various release profiles. Hot-melt extrusion was utilized to produce drug-loaded feedstock material that was subsequently 3D-printed into 6, 8, and 10 × 2.5 mm tablets with 15% and 90% infi...
Autores principales: | Öblom, Heidi, Zhang, Jiaxiang, Pimparade, Manjeet, Speer, Isabell, Preis, Maren, Repka, Michael, Sandler, Niklas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373414/ https://www.ncbi.nlm.nih.gov/pubmed/30617660 http://dx.doi.org/10.1208/s12249-018-1233-7 |
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