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Development and In Vivo Evaluation of Ziyuglycoside I–Loaded Self-Microemulsifying Formulation for Activity of Increasing Leukocyte

Ziyuglycoside I (ZgI), a major effective ingredient of Sanguisorba officinalis L, has shown good activity in increasing leukocyte of myelosuppression mice. However, oral ZgI therapy has been deterred by poor bioavailability because of its low aqueous solubility and permeability. Our study was to dev...

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Detalles Bibliográficos
Autores principales: Xiong, Yongai, Zou, Ya, Chen, Li, Xu, Yingshu, Wang, Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373417/
https://www.ncbi.nlm.nih.gov/pubmed/30721444
http://dx.doi.org/10.1208/s12249-019-1313-3