Reprogramming Captures the Genetic and Tumorigenic Properties of Neurofibromatosis Type 1 Plexiform Neurofibromas

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Neurofibromatosis type 1 (NF1) is a tumor predisposition genetic disease caused by mutations in the NF1 tumor suppressor gene. Plexiform neurofibromas (PNFs) are benign Schwann cell (SC) tumors of the peripheral nerve sheath that develop through NF1 inactivation and can progress toward a malignant s...

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Detalles Bibliográficos
Autores principales: Carrió, Meritxell, Mazuelas, Helena, Richaud-Patin, Yvonne, Gel, Bernat, Terribas, Ernest, Rosas, Imma, Jimenez-Delgado, Senda, Biayna, Josep, Vendredy, Leen, Blanco, Ignacio, Castellanos, Elisabeth, Lázaro, Conxi, Raya, Ángel, Serra, Eduard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373434/
https://www.ncbi.nlm.nih.gov/pubmed/30713041
http://dx.doi.org/10.1016/j.stemcr.2019.01.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373434/
https://www.ncbi.nlm.nih.gov/pubmed/30713041
http://dx.doi.org/10.1016/j.stemcr.2019.01.001

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