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Region-Restrict Astrocytes Exhibit Heterogeneous Susceptibility to Neuronal Reprogramming
The adult CNS has poor ability to replace degenerated neurons following injury or disease. Recently, direct reprogramming of astrocytes into induced neurons has been proposed as an innovative strategy toward CNS repair. As a cell population that shows high diversity on physiological properties and f...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373495/ https://www.ncbi.nlm.nih.gov/pubmed/30713039 http://dx.doi.org/10.1016/j.stemcr.2018.12.017 |