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Region-Restrict Astrocytes Exhibit Heterogeneous Susceptibility to Neuronal Reprogramming

The adult CNS has poor ability to replace degenerated neurons following injury or disease. Recently, direct reprogramming of astrocytes into induced neurons has been proposed as an innovative strategy toward CNS repair. As a cell population that shows high diversity on physiological properties and f...

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Detalles Bibliográficos
Autores principales: Hu, Xin, Qin, Shangyao, Huang, Xiao, Yuan, Yimin, Tan, Zijian, Gu, Yakun, Cheng, Xueyan, Wang, Dan, Lian, Xiao-Feng, He, Cheng, Su, Zhida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373495/
https://www.ncbi.nlm.nih.gov/pubmed/30713039
http://dx.doi.org/10.1016/j.stemcr.2018.12.017