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Sox10 Regulates Plasticity of Epithelial Progenitors toward Secretory Units of Exocrine Glands

Understanding how epithelial progenitors within exocrine glands establish specific cell lineages and form complex functional secretory units is vital for organ regeneration. Here we identify the transcription factor Sox10 as essential for both the maintenance and differentiation of epithelial KIT(+)...

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Detalles Bibliográficos
Autores principales: Athwal, Harleen K., Murphy, George, Tibbs, Ellis, Cornett, Ashley, Hill, Emily, Yeoh, Kenji, Berenstein, Elsa, Hoffman, Matthew P., Lombaert, Isabelle M.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373627/
https://www.ncbi.nlm.nih.gov/pubmed/30713042
http://dx.doi.org/10.1016/j.stemcr.2019.01.002