An adaptive geometric search algorithm for macromolecular scaffold selection

A wide variety of protein and peptidomimetic design tasks require matching functional 3D motifs to potential oligomeric scaffolds. For example, during enzyme design, one aims to graft active-site patterns—typically consisting of 3–15 residues—onto new protein surfaces. Identifying protein scaffolds...

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Detalles Bibliográficos
Autores principales: Jiang, Tian, Renfrew, P Douglas, Drew, Kevin, Youngs, Noah, Butterfoss, Glenn L, Bonneau, Richard, Shasha, Den Nis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373690/
https://www.ncbi.nlm.nih.gov/pubmed/30407584
http://dx.doi.org/10.1093/protein/gzy028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373690/
https://www.ncbi.nlm.nih.gov/pubmed/30407584
http://dx.doi.org/10.1093/protein/gzy028

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