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Clustered DNA double-strand break formation and the repair pathway following heavy-ion irradiation

Photons, such as X- or γ-rays, induce DNA damage (distributed throughout the nucleus) as a result of low-density energy deposition. In contrast, particle irradiation with high linear energy transfer (LET) deposits high-density energy along the particle track. High-LET heavy-ion irradiation generates...

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Detalles Bibliográficos
Autores principales: Hagiwara, Yoshihiko, Oike, Takahiro, Niimi, Atsuko, Yamauchi, Motohiro, Sato, Hiro, Limsirichaikul, Siripan, Held, Kathryn D, Nakano, Takashi, Shibata, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373698/
https://www.ncbi.nlm.nih.gov/pubmed/30476166
http://dx.doi.org/10.1093/jrr/rry096