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Clustered DNA double-strand break formation and the repair pathway following heavy-ion irradiation
Photons, such as X- or γ-rays, induce DNA damage (distributed throughout the nucleus) as a result of low-density energy deposition. In contrast, particle irradiation with high linear energy transfer (LET) deposits high-density energy along the particle track. High-LET heavy-ion irradiation generates...
Autores principales: | Hagiwara, Yoshihiko, Oike, Takahiro, Niimi, Atsuko, Yamauchi, Motohiro, Sato, Hiro, Limsirichaikul, Siripan, Held, Kathryn D, Nakano, Takashi, Shibata, Atsushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373698/ https://www.ncbi.nlm.nih.gov/pubmed/30476166 http://dx.doi.org/10.1093/jrr/rry096 |
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