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Ameliorative Effect of Coenzyme Q10 and/or Candesartan on Carboplatin-Induced Nephrotoxicity: Roles of Apoptosis, Transforming Growth Factor-Β1, Nuclear Factor Kappa-B And The Nrf2/HO-1 Pathway
BACKGROUND: Carboplatin is a drug that is used for treatment of many types of cancer. However, it may produce serious nephrotoxicity. Candesartan is angiotensin II receptor antagonist employed mainly for control of hypertension. Coenzyme Q10 (CoQ10) is a fat-soluble substance which was proven to hav...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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West Asia Organization for Cancer Prevention
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373792/ https://www.ncbi.nlm.nih.gov/pubmed/28670881 http://dx.doi.org/10.22034/APJCP.2017.18.6.1629 |