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Osteopontin b and c isoforms: Molecular Candidates Associated with Leukemic Stem Cell Chemoresistance in Acute Myeloid Leukemia

Despite impressive advances in therapeutic approaches, long-term survival with acute myeloid leukemia (AML) is low as a result of treatment resistance and frequent relapse. Among multitude oncogenic proteins involved in the acquisition of a chemo-resistant phenotype, osteopontin (OPN) recently has a...

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Detalles Bibliográficos
Autores principales: Mirzaei, Akram, Mohammadi, Saeed, Ghaffari, Seyed H, Nikbakht, Mohsen, Bashash, Davood, Alimoghaddam, Kamran, Ghavamzadeh, Ardeshir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373801/
https://www.ncbi.nlm.nih.gov/pubmed/28670893
http://dx.doi.org/10.22034/APJCP.2017.18.6.1707