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Convergent perturbation of the human domain-resolved interactome by viruses and mutations inducing similar disease phenotypes

An important goal of systems medicine is to study disease in the context of genetic and environmental perturbations to the human interactome network. For diseases with both genetic and infectious contributors, a key postulate is that similar perturbations of the human interactome by either disease m...

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Detalles Bibliográficos
Autores principales: Chen, Yangchun Frank, Xia, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373925/
https://www.ncbi.nlm.nih.gov/pubmed/30759076
http://dx.doi.org/10.1371/journal.pcbi.1006762