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Convergent perturbation of the human domain-resolved interactome by viruses and mutations inducing similar disease phenotypes
An important goal of systems medicine is to study disease in the context of genetic and environmental perturbations to the human interactome network. For diseases with both genetic and infectious contributors, a key postulate is that similar perturbations of the human interactome by either disease m...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373925/ https://www.ncbi.nlm.nih.gov/pubmed/30759076 http://dx.doi.org/10.1371/journal.pcbi.1006762 |