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Searching for the causal effects of body mass index in over 300 000 participants in UK Biobank, using Mendelian randomization

Mendelian randomization (MR) has been used to estimate the causal effect of body mass index (BMI) on particular traits thought to be affected by BMI. However, BMI may also be a modifiable, causal risk factor for outcomes where there is no prior reason to suggest that a causal effect exists. We perfo...

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Detalles Bibliográficos
Autores principales: Millard, Louise A. C., Davies, Neil M., Tilling, Kate, Gaunt, Tom R., Davey Smith, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373977/
https://www.ncbi.nlm.nih.gov/pubmed/30707692
http://dx.doi.org/10.1371/journal.pgen.1007951