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Macrophages restrict the nephrogenic field and promote endothelial connections during kidney development

The origins and functions of kidney macrophages in the adult have been explored, but their roles during development remain largely unknown. Here we characterise macrophage arrival, localisation, heterogeneity, and functions during kidney organogenesis. Using genetic approaches to ablate macrophages,...

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Detalles Bibliográficos
Autores principales: Munro, David AD, Wineberg, Yishay, Tarnick, Julia, Vink, Chris S, Li, Zhuan, Pridans, Clare, Dzierzak, Elaine, Kalisky, Tomer, Hohenstein, Peter, Davies, Jamie A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374076/
https://www.ncbi.nlm.nih.gov/pubmed/30758286
http://dx.doi.org/10.7554/eLife.43271