Free Polyethylenimine Enhances Substrate-Mediated Gene Delivery on Titanium Substrates Modified With RGD-Functionalized Poly(acrylic acid) Brushes

Substrate mediated gene delivery (SMD) is a method of immobilizing DNA complexes to a substrate via covalent attachment or nonspecific adsorption, which allows for increased transgene expression with less DNA compared to traditional bolus delivery. It may also increase cells receptivity to transfect...

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Detalles Bibliográficos
Autores principales: Mantz, Amy, Rosenthal, Alice, Farris, Eric, Kozisek, Tyler, Bittrich, Eva, Nazari, Saghar, Schubert, Eva, Schubert, Mathias, Stamm, Manfred, Uhlmann, Petra, Pannier, Angela K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374293/
https://www.ncbi.nlm.nih.gov/pubmed/30792979
http://dx.doi.org/10.3389/fchem.2019.00051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374293/
https://www.ncbi.nlm.nih.gov/pubmed/30792979
http://dx.doi.org/10.3389/fchem.2019.00051

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