Restoring T Cell Tolerance, Exploring the Potential of Histone Deacetylase Inhibitors for the Treatment of Juvenile Idiopathic Arthritis

Juvenile Idiopathic Arthritis (JIA) is characterized by a loss of immune tolerance. Here, the balance between the activity of effector T (Teff) cells and regulatory T (Treg) cells is disturbed resulting in chronic inflammation in the joints. Presently, therapeutic strategies are predominantly aimed...

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Detalles Bibliográficos
Autores principales: Nijhuis, Lotte, Peeters, Janneke G. C., Vastert, Sebastiaan J., van Loosdregt, Jorg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374297/
https://www.ncbi.nlm.nih.gov/pubmed/30792714
http://dx.doi.org/10.3389/fimmu.2019.00151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374297/
https://www.ncbi.nlm.nih.gov/pubmed/30792714
http://dx.doi.org/10.3389/fimmu.2019.00151

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