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Restoring T Cell Tolerance, Exploring the Potential of Histone Deacetylase Inhibitors for the Treatment of Juvenile Idiopathic Arthritis

Juvenile Idiopathic Arthritis (JIA) is characterized by a loss of immune tolerance. Here, the balance between the activity of effector T (Teff) cells and regulatory T (Treg) cells is disturbed resulting in chronic inflammation in the joints. Presently, therapeutic strategies are predominantly aimed...

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Detalles Bibliográficos
Autores principales:	Nijhuis, Lotte, Peeters, Janneke G. C., Vastert, Sebastiaan J., van Loosdregt, Jorg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374297/ https://www.ncbi.nlm.nih.gov/pubmed/30792714 http://dx.doi.org/10.3389/fimmu.2019.00151

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