1,25-Dihydroxyvitamin D3 Ameliorates Collagen-Induced Arthritis via Suppression of Th17 Cells Through miR-124 Mediated Inhibition of IL-6 Signaling

Objectives: To explore the molecular mechanisms in which vitamin D (VD) regulates T cells, especially Th17 cells in collagen-induced arthritis (CIA). Methods: DBA1/J mice induced for CIA were intraperitoneally treated with VD. CIA clinical symptoms and inflammatory responses including Th1/Th17/Tregs...

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Detalles Bibliográficos
Autores principales: Zhou, Li, Wang, Julie, Li, Jingren, Li, Ting, Chen, Yanming, June, Rayford R., Zheng, Song Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374300/
https://www.ncbi.nlm.nih.gov/pubmed/30792721
http://dx.doi.org/10.3389/fimmu.2019.00178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374300/
https://www.ncbi.nlm.nih.gov/pubmed/30792721
http://dx.doi.org/10.3389/fimmu.2019.00178

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