Cargando…

p16Ink4a Prevents the Activation of Aged Quiescent Dentate Gyrus Stem Cells by Physical Exercise

In the neurogenic niches—the dentate gyrus of the hippocampus and the subventricular zone (SVZ) adjacent to lateral ventricles—stem cells continue to divide during adulthood, generating progenitor cells and new neurons, and to self-renew, thus maintaining the stem cell pool. During aging, the number...

Descripción completa

Detalles Bibliográficos
Autores principales:	Micheli, Laura, D’Andrea, Giorgio, Ceccarelli, Manuela, Ferri, Alessandra, Scardigli, Raffaella, Tirone, Felice
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374340/ https://www.ncbi.nlm.nih.gov/pubmed/30792628 http://dx.doi.org/10.3389/fncel.2019.00010

Ejemplares similares

Transcriptome analysis reveals genes associated with stem cell activation by physical exercise in the dentate gyrus of aged p16Ink4a knockout mice
por: Micheli, Laura, et al.
Publicado: (2023)

Transcriptome Analysis in a Mouse Model of Premature Aging of Dentate Gyrus: Rescue of Alpha-Synuclein Deficit by Virus-Driven Expression or by Running Restores the Defective Neurogenesis
por: Micheli, Laura, et al.
Publicado: (2021)

Btg1 is Required to Maintain the Pool of Stem and Progenitor Cells of the Dentate Gyrus and Subventricular Zone
por: Farioli-Vecchioli, Stefano, et al.
Publicado: (2012)

Deletion of Btg1 Induces Prmt1-Dependent Apoptosis and Increased Stemness in Shh-Type Medulloblastoma Cells Without Affecting Tumor Frequency
por: Ceccarelli, Manuela, et al.
Publicado: (2020)

Interaction Between Neurogenic Stimuli and the Gene Network Controlling the Activation of Stem Cells of the Adult Neurogenic Niches, in Physiological and Pathological Conditions
por: Ceccarelli, Manuela, et al.
Publicado: (2020)

Suppression of Medulloblastoma Lesions by Forced Migration of Preneoplastic Precursor Cells with Intracerebellar Administration of the Chemokine Cxcl3
por: Ceccarelli, Manuela, et al.
Publicado: (2016)

Tumor Growth in the High Frequency Medulloblastoma Mouse Model Ptch1(+/−)/Tis21(KO) Has a Specific Activation Signature of the PI3K/AKT/mTOR Pathway and Is Counteracted by the PI3K Inhibitor MEN1611
por: Ceccarelli, Manuela, et al.
Publicado: (2021)

Reassessing pattern separation in the dentate gyrus
por: Santoro, Adam
Publicado: (2013)

Microelastic mapping of the rat dentate gyrus
por: Luque, Tomás, et al.
Publicado: (2016)

Sampling the Mouse Hippocampal Dentate Gyrus
por: Basler, Lisa, et al.
Publicado: (2017)

A septo-temporal molecular gradient of sfrp3 in the dentate gyrus differentially regulates quiescent adult hippocampal neural stem cell activation
por: Sun, Jiaqi, et al.
Publicado: (2015)

Functional circuits of new neurons in the dentate gyrus
por: Vivar, Carmen, et al.
Publicado: (2013)

Adult neurogenesis modifies excitability of the dentate gyrus
por: Ikrar, Taruna, et al.
Publicado: (2013)

Immature Dentate Gyrus: An Endophenotype of Neuropsychiatric Disorders
por: Hagihara, Hideo, et al.
Publicado: (2013)

The Role of Dentate Gyrus Neurogenesis in Neuropsychiatric Disorders
por: García-Fuster, M. Julia, et al.
Publicado: (2013)

The dentate gyrus in depression: directions for future research
por: Nuninga, Jasper O., et al.
Publicado: (2020)

Differential vulnerability of the dentate gyrus to tauopathies in dementias
por: Kawles, Allegra, et al.
Publicado: (2023)

Terminal Differentiation of Adult Hippocampal Progenitor Cells Is a Step Functionally Dissociable from Proliferation and Is Controlled by Tis21, Id3 and NeuroD2
por: Micheli, Laura, et al.
Publicado: (2017)

Tis21 is required for adult neurogenesis in the subventricular zone and for olfactory behavior regulating cyclins, BMP4, Hes1/5 and Ids
por: Farioli-Vecchioli, Stefano, et al.
Publicado: (2014)

Synapsin I and Synapsin II regulate neurogenesis in the dentate gyrus of adult mice
por: Barbieri, Raffaella, et al.
Publicado: (2018)

Functional Genomics Identifies Tis21-Dependent Mechanisms and Putative Cancer Drug Targets Underlying Medulloblastoma Shh-Type Development
por: Gentile, Giulia, et al.
Publicado: (2016)

An extrahippocampal projection from the dentate gyrus to the olfactory tubercle
por: Künzle, Heinz
Publicado: (2005)

Dissection of Hippocampal Dentate Gyrus from Adult Mouse
por: Hagihara, Hideo, et al.
Publicado: (2009)

Short-Term Synaptic Plasticity in the Dentate Gyrus of Monkeys
por: Tamura, Ryoi, et al.
Publicado: (2011)

Neurogenesis in the dentate gyrus: carrying the message or dictating the tone
por: Piatti, Verónica C., et al.
Publicado: (2013)

Structure, function, and plasticity of hippocampal dentate gyrus microcircuits
por: Jonas, Peter, et al.
Publicado: (2014)

Adult neurogenesis in the mammalian hippocampus: Why the dentate gyrus?
por: Drew, Liam J., et al.
Publicado: (2013)

Temporally selective contextual encoding in the dentate gyrus of the hippocampus
por: Rangel, L.M., et al.
Publicado: (2014)

Differential Involvement of the Dentate Gyrus in Adaptive Forgetting in the Rat
por: Joseph, Mickaël Antoine, et al.
Publicado: (2015)

Neuromodulation of the Feedforward Dentate Gyrus-CA3 Microcircuit
por: Prince, Luke Y., et al.
Publicado: (2016)

Stimulation of entorhinal cortex-dentate gyrus circuitry is antidepressive
por: Yun, Sanghee, et al.
Publicado: (2018)

The Dentate Gyrus and Temporal Lobe Epilepsy: An “Exciting” Era
por: Scharfman, Helen E.
Publicado: (2019)

Anatomical variations of the dentate gyrus in normal adult brain
por: Haładaj, Robert
Publicado: (2019)

Dentate gyrus activin signaling mediates the antidepressant response
por: Gergues, Mark M., et al.
Publicado: (2021)

Synchronous activity patterns in the dentate gyrus during immobility
por: Pofahl, Martin, et al.
Publicado: (2021)

Correction: The dentate gyrus in depression: directions for future research
por: Nuninga, Jasper O., et al.
Publicado: (2020)

Research on Network Model of Dentate Gyrus Based on Bionics
por: Zhang, Jin, et al.
Publicado: (2021)

A functional model of adult dentate gyrus neurogenesis
por: Gozel, Olivia, et al.
Publicado: (2021)

Microstructural mapping of dentate gyrus pathology in Alzheimer’s disease: A 16.4 Tesla MRI study
por: Shih, Nien-Chu, et al.
Publicado: (2023)

Genetic control of adult neurogenesis: interplay of differentiation, proliferation and survival modulates new neurons function, and memory circuits
por: Tirone, Felice, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_77vqln9vm9sh6bomsc0prkllt4