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Overproduction of Phospholipids by the Kennedy Pathway Leads to Hypervirulence in Candida albicans

Candida albicans is an opportunistic human fungal pathogen that causes life-threatening systemic infections, as well as oral mucosal infections. Phospholipids are crucial for pathogenesis in C. albicans, as disruption of phosphatidylserine (PS) and phosphatidylethanolamine (PE) biosynthesis within t...

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Detalles Bibliográficos
Autores principales: Tams, Robert N., Cassilly, Chelsi D., Anaokar, Sanket, Brewer, William T., Dinsmore, Justin T., Chen, Ying-Lien, Patton-Vogt, Jana, Reynolds, Todd B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374345/
https://www.ncbi.nlm.nih.gov/pubmed/30792701
http://dx.doi.org/10.3389/fmicb.2019.00086