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Overproduction of Phospholipids by the Kennedy Pathway Leads to Hypervirulence in Candida albicans
Candida albicans is an opportunistic human fungal pathogen that causes life-threatening systemic infections, as well as oral mucosal infections. Phospholipids are crucial for pathogenesis in C. albicans, as disruption of phosphatidylserine (PS) and phosphatidylethanolamine (PE) biosynthesis within t...
Autores principales: | Tams, Robert N., Cassilly, Chelsi D., Anaokar, Sanket, Brewer, William T., Dinsmore, Justin T., Chen, Ying-Lien, Patton-Vogt, Jana, Reynolds, Todd B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374345/ https://www.ncbi.nlm.nih.gov/pubmed/30792701 http://dx.doi.org/10.3389/fmicb.2019.00086 |
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