The Alteration of Intrinsic Excitability and Synaptic Transmission in Lumbar Spinal Motor Neurons and Interneurons of Severe Spinal Muscular Atrophy Mice

Spinal muscular atrophy (SMA) is the leading genetic cause of death in infants. Studies with mouse models have demonstrated increased excitability and loss of afferent proprioceptive synapses on motor neurons (MNs). To further understand functional changes in the motor neural network occurring in SM...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Jianli, Harrington, Melissa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374350/
https://www.ncbi.nlm.nih.gov/pubmed/30792629
http://dx.doi.org/10.3389/fncel.2019.00015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374350/
https://www.ncbi.nlm.nih.gov/pubmed/30792629
http://dx.doi.org/10.3389/fncel.2019.00015

Ejemplares similares