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Induction of GNMT by 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranoside through proteasome-independent MYC downregulation in hepatocellular carcinoma
Glycine-N-methyl transferase (GNMT) a tumor suppressor for hepatocellular carcinoma (HCC) plays a crucial role in liver homeostasis. Its expression is downregulated in almost all the tumor tissues of HCC while the mechanism of this downregulation is not yet fully understood. Recently, we identified...
Autores principales: | Kant, Rajni, Yen, Chia-Hung, Hung, Jung-Hsien, Lu, Chung-Kuang, Tung, Chien-Yi, Chang, Pei-Ching, Chen, Yueh-Hao, Tyan, Yu-Chang, Chen, Yi-Ming Arthur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374375/ https://www.ncbi.nlm.nih.gov/pubmed/30760754 http://dx.doi.org/10.1038/s41598-018-37292-1 |
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