Fisetin induces autophagy in pancreatic cancer cells via endoplasmic reticulum stress- and mitochondrial stress-dependent pathways

Pancreatic cancer is one of the most aggressive tumors and patients have poor survival rates. Fisetin, a natural flavonoid, was recently reported to have antitumor effects in various cancer models. Autophagy is a conserved catabolic process that maintains cellular homoeostasis in response to stress,...

Descripción completa

Detalles Bibliográficos
Autores principales: Jia, Shengnan, Xu, Xiaodong, Zhou, Senhao, Chen, Yan, Ding, Guoping, Cao, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374379/
https://www.ncbi.nlm.nih.gov/pubmed/30760707
http://dx.doi.org/10.1038/s41419-019-1366-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374379/
https://www.ncbi.nlm.nih.gov/pubmed/30760707
http://dx.doi.org/10.1038/s41419-019-1366-y

Ejemplares similares