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Fisetin induces autophagy in pancreatic cancer cells via endoplasmic reticulum stress- and mitochondrial stress-dependent pathways
Pancreatic cancer is one of the most aggressive tumors and patients have poor survival rates. Fisetin, a natural flavonoid, was recently reported to have antitumor effects in various cancer models. Autophagy is a conserved catabolic process that maintains cellular homoeostasis in response to stress,...
Autores principales: | Jia, Shengnan, Xu, Xiaodong, Zhou, Senhao, Chen, Yan, Ding, Guoping, Cao, Liping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374379/ https://www.ncbi.nlm.nih.gov/pubmed/30760707 http://dx.doi.org/10.1038/s41419-019-1366-y |
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