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Attenuated Lymphatic Proliferation Ameliorates Diabetic Nephropathy and High-Fat Diet-Induced Renal Lipotoxicity

Lymphangiogenesis occurs in response to renal injury and is correlated with interstitial fibrosis. Diabetes- and high-fat diet (HFD)-induced intrarenal lipotoxicity and their relationships with lymphangiogenesis are not established. We used PPARα agonist, fenofibrate, to unravel the linkage between...

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Detalles Bibliográficos
Autores principales: Kim, Yaeni, Hwang, Seun Deuk, Lim, Ji Hee, Kim, Min Young, Kim, Eun Nim, Choi, Bum Soon, Kim, Yong-Soo, Kim, Hye Won, Park, Cheol Whee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374395/
https://www.ncbi.nlm.nih.gov/pubmed/30760777
http://dx.doi.org/10.1038/s41598-018-38250-7