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Inactive Tlk associating with Tak1 increases p38 MAPK activity to prolong the G2 phase
To guard genome integrity, response mechanisms coordinately execute the G2/M checkpoint in responding to stress. p38 MAPK is activated to prolong the G2 phase for completion of damage repair. Tlk activity is required for DNA repair, chromosome segregation and G2 recovery. However, the involvement of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374402/ https://www.ncbi.nlm.nih.gov/pubmed/30760733 http://dx.doi.org/10.1038/s41598-018-36137-1 |