Site-specific manipulation of Arabidopsis loci using CRISPR-Cas9 SunTag systems

Understanding genomic functions requires site-specific manipulation of loci via efficient protein effector targeting systems. However, few approaches for targeted manipulation of the epigenome are available in plants. Here, we adapt the dCas9-SunTag system to engineer targeted gene activation and DN...

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Detalles Bibliográficos
Autores principales: Papikian, Ashot, Liu, Wanlu, Gallego-Bartolomé, Javier, Jacobsen, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374409/
https://www.ncbi.nlm.nih.gov/pubmed/30760722
http://dx.doi.org/10.1038/s41467-019-08736-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374409/
https://www.ncbi.nlm.nih.gov/pubmed/30760722
http://dx.doi.org/10.1038/s41467-019-08736-7

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