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Site-specific manipulation of Arabidopsis loci using CRISPR-Cas9 SunTag systems
Understanding genomic functions requires site-specific manipulation of loci via efficient protein effector targeting systems. However, few approaches for targeted manipulation of the epigenome are available in plants. Here, we adapt the dCas9-SunTag system to engineer targeted gene activation and DN...
Autores principales: | Papikian, Ashot, Liu, Wanlu, Gallego-Bartolomé, Javier, Jacobsen, Steven E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374409/ https://www.ncbi.nlm.nih.gov/pubmed/30760722 http://dx.doi.org/10.1038/s41467-019-08736-7 |
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