L-PGDS-produced PGD(2) in premature, but not in mature, adipocytes increases obesity and insulin resistance

Lipocalin-type prostaglandin (PG) D synthase (L-PGDS) is responsible for the production of PGD(2) in adipocytes and is selectively induced by a high-fat diet (HFD) in adipose tissue. In this study, we investigated the effects of HFD on obesity and insulin resistance in two distinct types of adipose-...

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Detalles Bibliográficos
Autores principales: Fujimori, Ko, Aritake, Kosuke, Oishi, Yo, Nagata, Nanae, Maehara, Toko, Lazarus, Michael, Urade, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374461/
https://www.ncbi.nlm.nih.gov/pubmed/30760783
http://dx.doi.org/10.1038/s41598-018-38453-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374461/
https://www.ncbi.nlm.nih.gov/pubmed/30760783
http://dx.doi.org/10.1038/s41598-018-38453-y

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