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L-PGDS-produced PGD(2) in premature, but not in mature, adipocytes increases obesity and insulin resistance

Lipocalin-type prostaglandin (PG) D synthase (L-PGDS) is responsible for the production of PGD(2) in adipocytes and is selectively induced by a high-fat diet (HFD) in adipose tissue. In this study, we investigated the effects of HFD on obesity and insulin resistance in two distinct types of adipose-...

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Detalles Bibliográficos
Autores principales:	Fujimori, Ko, Aritake, Kosuke, Oishi, Yo, Nagata, Nanae, Maehara, Toko, Lazarus, Michael, Urade, Yoshihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374461/ https://www.ncbi.nlm.nih.gov/pubmed/30760783 http://dx.doi.org/10.1038/s41598-018-38453-y

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