Tumorigenicity assay essential for facilitating safety studies of hiPSC-derived cardiomyocytes for clinical application

Transplantation of cardiomyocytes (CMs) derived from human induced pluripotent stem cells (hiPSC-CMs) is a promising treatment for heart failure, but residual undifferentiated hiPSCs and malignant transformed cells may lead to tumor formation. Here we describe a highly sensitive tumorigenicity assay...

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Detalles Bibliográficos
Autores principales: Ito, Emiko, Miyagawa, Shigeru, Takeda, Maki, Kawamura, Ai, Harada, Akima, Iseoka, Hiroko, Yajima, Shin, Sougawa, Nagako, Mochizuki-Oda, Noriko, Yasuda, Satoshi, Sato, Yoji, Sawa, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374479/
https://www.ncbi.nlm.nih.gov/pubmed/30760836
http://dx.doi.org/10.1038/s41598-018-38325-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374479/
https://www.ncbi.nlm.nih.gov/pubmed/30760836
http://dx.doi.org/10.1038/s41598-018-38325-5

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