DRUGPATH – a novel bioinformatic approach identifies DNA-damage pathway as a regulator of size maintenance in human ESCs and iPSCs

Genetic and biochemical screening approaches often fail to identify functionally relevant pathway networks because many signaling proteins contribute to multiple gene ontology pathways. We developed a DRUGPATH-approach to predict pathway-interactomes from high-content drug screen data. DRUGPATH is b...

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Detalles Bibliográficos
Autores principales: Kovacic, Boris, Rosner, Margit, Schlangen, Karin, Kramer, Nina, Hengstschläger, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374489/
https://www.ncbi.nlm.nih.gov/pubmed/30760778
http://dx.doi.org/10.1038/s41598-018-37491-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374489/
https://www.ncbi.nlm.nih.gov/pubmed/30760778
http://dx.doi.org/10.1038/s41598-018-37491-w

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