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Polygenic risk for neuropsychiatric disease and vulnerability to abnormal deep grey matter development

Neuropsychiatric disease has polygenic determinants but is often precipitated by environmental pressures, including adverse perinatal events. However, the way in which genetic vulnerability and early-life adversity interact remains obscure. We hypothesised that the extreme environmental stress of pr...

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Detalles Bibliográficos
Autores principales: Cullen, Harriet, Krishnan, Michelle L., Selzam, Saskia, Ball, Gareth, Visconti, Alessia, Saxena, Alka, Counsell, Serena J., Hajnal, Jo, Breen, Gerome, Plomin, Robert, Edwards, A. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374514/
https://www.ncbi.nlm.nih.gov/pubmed/30760829
http://dx.doi.org/10.1038/s41598-019-38957-1