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Polygenic risk for neuropsychiatric disease and vulnerability to abnormal deep grey matter development
Neuropsychiatric disease has polygenic determinants but is often precipitated by environmental pressures, including adverse perinatal events. However, the way in which genetic vulnerability and early-life adversity interact remains obscure. We hypothesised that the extreme environmental stress of pr...
Autores principales: | Cullen, Harriet, Krishnan, Michelle L., Selzam, Saskia, Ball, Gareth, Visconti, Alessia, Saxena, Alka, Counsell, Serena J., Hajnal, Jo, Breen, Gerome, Plomin, Robert, Edwards, A. David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374514/ https://www.ncbi.nlm.nih.gov/pubmed/30760829 http://dx.doi.org/10.1038/s41598-019-38957-1 |
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