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Phencynonate S-isomer as a eutomer is a novel central anticholinergic drug for anti-motion sickness
To compare and evaluate the differences of stereoselective activity, the binding affinity, metabolism, transport and molecular docking of phencynonate isomers to muscarinic acetylcholine receptor (mAChR) were investigated in this study. The rotation stimulation and locomotor experiments were used to...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374516/ https://www.ncbi.nlm.nih.gov/pubmed/30760797 http://dx.doi.org/10.1038/s41598-018-38305-9 |