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Targeted Gene Delivery into the Mammalian Inner Ear Using Synthetic Serotypes of Adeno-Associated Virus Vectors

Targeting specific cell types in the mammalian inner ear is important for treating genetic hearing loss due to the different cell type-specific functions. Adeno-associated virus (AAV) is an efficient in vivo gene transfer vector, and it has demonstrated promise for treating genetic hearing loss. Alt...

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Detalles Bibliográficos
Autores principales: Kim, Min-A, Ryu, Nari, Kim, Hye-Min, Kim, Ye-Ri, Lee, Byeonghyeon, Kwon, Tae-Jun, Bok, Jinwoong, Kim, Un-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374519/
https://www.ncbi.nlm.nih.gov/pubmed/30805407
http://dx.doi.org/10.1016/j.omtm.2019.01.002