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Web-based display of protein surface and pH-dependent properties for assessing the developability of biotherapeutics
Protein instability leads to reversible self-association and irreversible aggregation which is a major concern for developing new biopharmaceutical leads. Protein solution behaviour is dictated by the physicochemical properties of the protein and the solution. Optimising protein solutions through ex...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374528/ https://www.ncbi.nlm.nih.gov/pubmed/30760735 http://dx.doi.org/10.1038/s41598-018-36950-8 |