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Effect of Age, High-Fat Diet, and Rat Strain on Serum Biomarkers and Telomere Length and Global DNA Methylation in Peripheral Blood Mononuclear Cells

The objective of the current study was to determine if age, diet, and genetic disposition (animal strain) in an animal model had early effects on specific molecular markers in circulating peripheral blood mononuclear cells (PBMCs). Three strains [Sprague-Dawley (SD), Fischer 344 (F344), and Brown-No...

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Detalles Bibliográficos
Autores principales: Antonini, James M., Kodali, Vamsi, Meighan, Terence G., Roach, Katherine A., Roberts, Jenny R., Salmen, Rebecca, Boyce, Greg R., Zeidler-Erdely, Patti C., Kashon, Michael, Erdely, Aaron, Shoeb, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374545/
https://www.ncbi.nlm.nih.gov/pubmed/30760804
http://dx.doi.org/10.1038/s41598-018-38192-0