Cargando…

Effect of Age, High-Fat Diet, and Rat Strain on Serum Biomarkers and Telomere Length and Global DNA Methylation in Peripheral Blood Mononuclear Cells

The objective of the current study was to determine if age, diet, and genetic disposition (animal strain) in an animal model had early effects on specific molecular markers in circulating peripheral blood mononuclear cells (PBMCs). Three strains [Sprague-Dawley (SD), Fischer 344 (F344), and Brown-No...

Descripción completa

Detalles Bibliográficos
Autores principales:	Antonini, James M., Kodali, Vamsi, Meighan, Terence G., Roach, Katherine A., Roberts, Jenny R., Salmen, Rebecca, Boyce, Greg R., Zeidler-Erdely, Patti C., Kashon, Michael, Erdely, Aaron, Shoeb, Mohammad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374545/ https://www.ncbi.nlm.nih.gov/pubmed/30760804 http://dx.doi.org/10.1038/s41598-018-38192-0

Ejemplares similares

Using liquid chromatography mass spectrometry (LC-MS) to assess the effect of age, high-fat diet, and rat strain on the liver metabolome
por: Boyce, Greg, et al.
Publicado: (2020)

Welding fume inhalation exposure and high-fat diet change lipid homeostasis in rat liver
por: Boyce, Greg R., et al.
Publicado: (2020)

Oxidative stress and reduced responsiveness of challenged circulating leukocytes following pulmonary instillation of metal-rich particulate matter in rats
por: Erdely, Aaron, et al.
Publicado: (2014)

Silica inhalation altered telomere length and gene expression of telomere regulatory proteins in lung tissue of rats
por: Shoeb, Mohammad, et al.
Publicado: (2017)

Lung tumor promotion by chromium-containing welding particulate matter in a mouse model
por: Zeidler-Erdely, Patti C, et al.
Publicado: (2013)

Initiation of Pulmonary Fibrosis after Silica Inhalation in Rats is linked with Dysfunctional Shelterin Complex and DNA Damage Response
por: Shoeb, Mohammad, et al.
Publicado: (2019)

Pulmonary toxicity and lung tumorigenic potential of surrogate metal oxides in gas metal arc welding–stainless steel fume: Iron as a primary mediator versus chromium and nickel
por: Falcone, Lauryn M., et al.
Publicado: (2018)

Pulmonary inflammation and tumor induction in lung tumor susceptible A/J and resistant C57BL/6J mice exposed to welding fume
por: Zeidler-Erdely, Patti C, et al.
Publicado: (2008)

Response of the mouse lung transcriptome to welding fume: effects of stainless and mild steel fumes on lung gene expression in A/J and C57BL/6J mice
por: Zeidler-Erdely, Patti C, et al.
Publicado: (2010)

Type I interferon and pattern recognition receptor signaling following particulate matter inhalation
por: Erdely, Aaron, et al.
Publicado: (2012)

Aerosol characterization and pulmonary responses in rats after short-term inhalation of fumes generated during resistance spot welding of galvanized steel
por: Antonini, James M., et al.
Publicado: (2017)

Inhalation of welding fumes reduced sperm counts and high fat diet reduced testosterone levels; differential effects in Sprague Dawley and Brown Norway rats
por: Skovmand, Astrid, et al.
Publicado: (2020)

Oxidant-induced epithelial alarmin pathway mediates lung inflammation and functional decline following ultrafine carbon and ozone inhalation co-exposure
por: Majumder, Nairrita, et al.
Publicado: (2021)

Arginase Activities and Global Arginine Bioavailability in Wild-Type and ApoE-Deficient Mice: Responses to High Fat and High Cholesterol Diets
por: Erdely, Aaron, et al.
Publicado: (2010)

In vitro cytotoxicity of Manville Code 100 glass fibers: Effect of fiber length on human alveolar macrophages
por: Zeidler-Erdely, Patti C, et al.
Publicado: (2006)

Nanoparticle exposure driven circulating bioactive peptidome causes systemic inflammation and vascular dysfunction
por: Mostovenko, Ekaterina, et al.
Publicado: (2019)

Carbon nanotube dosimetry: from workplace exposure assessment to inhalation toxicology
por: Erdely, Aaron, et al.
Publicado: (2013)

Influence of Amalaki Rasayana on telomerase activity and telomere length in human blood mononuclear cells
por: Guruprasad, Kanive P., et al.
Publicado: (2017)

Relationship of Telomere Length to Fat Redistribution in HIV
por: Iyengar, Sanjna, et al.
Publicado: (2020)

Histopathology of the broad class of carbon nanotubes and nanofibers used or produced in U.S. facilities in a murine model
por: Fraser, Kelly, et al.
Publicado: (2021)

Evaluation of the Pulmonary Toxicity of a Fume Generated from a Nickel-, Copper-Based Electrode to be Used as a Substitute in Stainless Steel Welding
por: Antonini, James M, et al.
Publicado: (2014)

Oxidized carbon black nanoparticles induce endothelial damage through C-X-C chemokine receptor 3-mediated pathway
por: Majumder, Nairrita, et al.
Publicado: (2021)

The relationship between peripheral blood mononuclear cells telomere length and diet - unexpected effect of red meat
por: Kasielski, Marek, et al.
Publicado: (2016)

Antipsychotics preserve telomere length in peripheral blood mononuclear cells after acute oxidative stress injury
por: Polho, Gabriel B., et al.
Publicado: (2021)

Telomere length heterogeneity in placenta revealed with high-resolution telomere length analysis
por: Garcia-Martin, I., et al.
Publicado: (2017)

Development of a thermal spray coating aerosol generator and inhalation exposure system
por: Afshari, Aliakbar A., et al.
Publicado: (2022)

Alcohol consumption and leukocyte telomere length
por: Dixit, Shalini, et al.
Publicado: (2019)

Thermal Expansion of a Multiphase Intermetallic Ti-Al-Nb-Mo Alloy Studied by High-Energy X-ray Diffraction
por: Staron, Peter, et al.
Publicado: (2021)

Milk Fat Intake and Telomere Length in U.S. Women and Men: The Role of the Milk Fat Fraction
por: Tucker, Larry A.
Publicado: (2019)

Newborn telomere length predicts later life telomere length: Tracking telomere length from birth to child- and adulthood
por: Martens, Dries S., et al.
Publicado: (2021)

Telomere Length and Bipolar Disorder
por: Powell, Timothy R, et al.
Publicado: (2018)

Telomere Length and Bipolar Disorder
por: Powell, Timothy R, et al.
Publicado: (2018)

Increased telomere length and proliferative potential in peripheral blood mononuclear cells of adults of different ages stimulated with concanavalin A
por: Murillo-Ortiz, Blanca, et al.
Publicado: (2013)

Telomere length and reproductive aging
por: Hanna, Courtney W., et al.
Publicado: (2009)

Telomeres and Telomere Length: A General Overview
por: Srinivas, Nalini, et al.
Publicado: (2020)

Telomere Length Regulation
por: Lansdorp, Peter
Publicado: (2022)

Physicochemical characterization and genotoxicity of the broad class of carbon nanotubes and nanofibers used or produced in U.S. facilities
por: Fraser, Kelly, et al.
Publicado: (2020)

Telomere length and human hippocampal neurogenesis
por: Palmos, Alish B., et al.
Publicado: (2020)

Mammalian chromosome–telomere length dynamics
por: Klegarth, Amy R., et al.
Publicado: (2018)

Evaluation of pulmonary and systemic toxicity following lung exposure to graphite nanoplates: a member of the graphene-based nanomaterial family
por: Roberts, Jenny R., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_iuvrtaqodal3tu7ogudug4q5d8