Rapamycin as a potential treatment for succinate dehydrogenase deficiency

Drosophila melanogaster is a powerful model to study mitochondrial respiratory chain defects, particularly succinate dehydrogenase (SDH) deficiency. Mutations in sdh genes cause degenerative disorders and often lead to death. Therapies for such pathologies are based on a combination of vitamins and...

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Detalles Bibliográficos
Autores principales: Fan, Frances, Sam, Rheba, Ryan, Emma, Alvarado, Katherine, Villa-Cuesta, Eugenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374580/
https://www.ncbi.nlm.nih.gov/pubmed/30805566
http://dx.doi.org/10.1016/j.heliyon.2019.e01217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374580/
https://www.ncbi.nlm.nih.gov/pubmed/30805566
http://dx.doi.org/10.1016/j.heliyon.2019.e01217

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