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Rapamycin as a potential treatment for succinate dehydrogenase deficiency
Drosophila melanogaster is a powerful model to study mitochondrial respiratory chain defects, particularly succinate dehydrogenase (SDH) deficiency. Mutations in sdh genes cause degenerative disorders and often lead to death. Therapies for such pathologies are based on a combination of vitamins and...
Autores principales: | Fan, Frances, Sam, Rheba, Ryan, Emma, Alvarado, Katherine, Villa-Cuesta, Eugenia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374580/ https://www.ncbi.nlm.nih.gov/pubmed/30805566 http://dx.doi.org/10.1016/j.heliyon.2019.e01217 |
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