A Controlled Human Infection Model of Group A Streptococcus Pharyngitis: Which Strain and Why?

Group A Streptococcus (GAS) is a major cause of global infection-related morbidity and mortality. A modern controlled human infection model (CHIM) of GAS pharyngitis can accelerate vaccine development and pathogenesis research. A robust rationale for strain selection is central to meeting ethical, s...

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Detalles Bibliográficos
Autores principales: Osowicki, Joshua, Azzopardi, Kristy I., McIntyre, Liam, Rivera-Hernandez, Tania, Ong, Cheryl-lynn Y., Baker, Ciara, Gillen, Christine M., Walker, Mark J., Smeesters, Pierre R., Davies, Mark R., Steer, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374595/
https://www.ncbi.nlm.nih.gov/pubmed/30760615
http://dx.doi.org/10.1128/mSphere.00647-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374595/
https://www.ncbi.nlm.nih.gov/pubmed/30760615
http://dx.doi.org/10.1128/mSphere.00647-18

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