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Phosphodiesterase 1b (PDE1B) Regulates Spatial and Contextual Memory in Hippocampus

Augmentation of cyclic nucleotide signaling through inhibition of phosphodiesterase (PDE) activity has long been understood to enhance memory. Efforts in this domain have focused predominantly on PDE4, a cAMP-specific phosphodiesterase implicated in consolidation. But less is known about the functio...

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Detalles Bibliográficos
Autores principales: McQuown, Susan, Xia, Shouzhen, Baumgärtel, Karsten, Barido, Richard, Anderson, Gary, Dyck, Brian, Scott, Roderick, Peters, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374598/
https://www.ncbi.nlm.nih.gov/pubmed/30792627
http://dx.doi.org/10.3389/fnmol.2019.00021