microRNA-34a (miRNA-34a) Mediated Down-Regulation of the Post-synaptic Cytoskeletal Element SHANK3 in Sporadic Alzheimer's Disease (AD)

Integrating a combination of bioinformatics, microRNA microfluidic arrays, ELISA analysis, LED Northern, and transfection-luciferase reporter assay data using human neuronal-glial (HNG) cells in primary culture we have discovered a set of up-regulated microRNAs (miRNAs) linked to a small family of d...

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Detalles Bibliográficos
Autores principales: Zhao, Yuhai, Jaber, Vivian R., LeBeauf, Ayrian, Sharfman, Nathan M., Lukiw, Walter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374620/
https://www.ncbi.nlm.nih.gov/pubmed/30792687
http://dx.doi.org/10.3389/fneur.2019.00028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374620/
https://www.ncbi.nlm.nih.gov/pubmed/30792687
http://dx.doi.org/10.3389/fneur.2019.00028

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