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microRNA-34a (miRNA-34a) Mediated Down-Regulation of the Post-synaptic Cytoskeletal Element SHANK3 in Sporadic Alzheimer's Disease (AD)
Integrating a combination of bioinformatics, microRNA microfluidic arrays, ELISA analysis, LED Northern, and transfection-luciferase reporter assay data using human neuronal-glial (HNG) cells in primary culture we have discovered a set of up-regulated microRNAs (miRNAs) linked to a small family of d...
Autores principales: | Zhao, Yuhai, Jaber, Vivian R., LeBeauf, Ayrian, Sharfman, Nathan M., Lukiw, Walter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374620/ https://www.ncbi.nlm.nih.gov/pubmed/30792687 http://dx.doi.org/10.3389/fneur.2019.00028 |
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