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Interferon-γ Receptor Signaling in Dendritic Cells Restrains Spontaneous Proliferation of CD4(+) T Cells in Chronic Lymphopenic Mice

In lymphopenic mice, T cells become activated and undergo lymphopenia-induced proliferation (LIP). However, not all T cells are equally sensitive to lymphopenia. Several lymphopenia-insensitive T cell clones were described and their non-responsiveness was mainly attributed to clone-specific properti...

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Detalles Bibliográficos
Autores principales: Knop, Laura, Frommer, Charlotte, Stoycheva, Diana, Deiser, Katrin, Kalinke, Ulrich, Blankenstein, Thomas, Kammertoens, Thomas, Dunay, Ildiko Rita, Schüler, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374634/
https://www.ncbi.nlm.nih.gov/pubmed/30792713
http://dx.doi.org/10.3389/fimmu.2019.00140