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Response to trametinib in recurrent low-grade serous ovarian cancer with NRAS mutation: A case report

Low-grade serous ovarian cancer represents a minority of ovarian cancers and has distinctive features from high grade epithelial ovarian cancer. While less aggressive, in advanced stage they can be poorly chemo-responsive and incur a treatment challenge. Next generation sequencing of tumors has allo...

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Detalles Bibliográficos
Autores principales: Champer, Miriam, Miller, Devin, Kuo, Dennis Yi-Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374783/
https://www.ncbi.nlm.nih.gov/pubmed/30809568
http://dx.doi.org/10.1016/j.gore.2019.01.007