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Downregulation of PTPRK Promotes Cell Proliferation and Metastasis of NSCLC by Enhancing STAT3 Activation

OBJECTIVE: The receptor-type tyrosine-protein phosphatase κ (PTPRK) is a candidate tumor suppressor involved in the tumorigenesis of various organs. However, its expression and biological roles in non-small-cell lung cancer (NSCLC) have not yet been investigated. METHODS: PTPRK expression in NSCLC t...

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Detalles Bibliográficos
Autores principales: Xu, Xuting, Li, Dong, Liu, Jin, Ma, Zhihong, Huang, Huilian, Min, Lishan, Dai, Licheng, Dong, Shunli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374804/
https://www.ncbi.nlm.nih.gov/pubmed/30838170
http://dx.doi.org/10.1155/2019/4265040