Cargando…
Downregulation of PTPRK Promotes Cell Proliferation and Metastasis of NSCLC by Enhancing STAT3 Activation
OBJECTIVE: The receptor-type tyrosine-protein phosphatase κ (PTPRK) is a candidate tumor suppressor involved in the tumorigenesis of various organs. However, its expression and biological roles in non-small-cell lung cancer (NSCLC) have not yet been investigated. METHODS: PTPRK expression in NSCLC t...
Autores principales: | Xu, Xuting, Li, Dong, Liu, Jin, Ma, Zhihong, Huang, Huilian, Min, Lishan, Dai, Licheng, Dong, Shunli |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374804/ https://www.ncbi.nlm.nih.gov/pubmed/30838170 http://dx.doi.org/10.1155/2019/4265040 |
Ejemplares similares
-
Identification of Hub Genes as Biomarkers Correlated with the Proliferation and Prognosis in Lung Cancer: A Weighted Gene Co-Expression Network Analysis
por: Xu, Xuting, et al.
Publicado: (2020) -
The homophilic receptor PTPRK selectively dephosphorylates multiple junctional regulators to promote cell–cell adhesion
por: Fearnley, Gareth W, et al.
Publicado: (2019) -
The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer
por: Chang, Ling-Shih, et al.
Publicado: (2020) -
PTPRK, an EGFR Phosphatase, Is Decreased in CeD Biopsies and Intestinal Organoids
por: Nanayakkara, Merlin, et al.
Publicado: (2022) -
The Impact of PTPRK and ROS1 Polymorphisms on the Preeclampsia Risk in Han Chinese Women
por: Li, Huihui, et al.
Publicado: (2021)